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Article

Opposite effects of Activin type 2 receptor ligands on cardiomyocyte proliferation during development and repair

27 Nov 2017

Abstract excerpt

Zebrafish regenerate damaged myocardial tissue very effectively. Hence, insights into the molecular networks underlying zebrafish heart regeneration might help develop alternative strategies to restore human cardiac performance. While TGF-β signaling has been implicated in zebrafish cardiac regeneration, the role of its individual ligands remains unclear. Here, we report the opposing expression response during...

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PMID: 29196619
DOI: 10.1038/s41467-017-01950-1

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