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Article

CYP3A4*22 and CYP3A combined genotypes both correlate with tacrolimus disposition in pediatric heart transplant recipients.

Pharmacogenomics - 1 Jul 2013

Gijsen Violette M G J, van Schaik Ron Hn, Elens Laure, Soldin Offie P, Soldin Steven J, Koren Gideon, de Wildt Saskia N

Abstract excerpt

BACKGROUND: Tacrolimus metabolism depends on CYP3A4 and CYP3A5. We aimed to determine the relationship between the CYP3A4*22 polymorphism and combined CYP3A genotypes with tacrolimus disposition in pediatric heart transplant recipients. METHODS: Sixty pediatric heart transplant recipients were in...

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Source

Identifiers

PMID: 23837477
DOI: 10.2217/pgs.13.80

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23837477-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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CYP3A4*22 and CYP3A combined genotypes both correlate with tacrolimus disposition in pediatric heart transplant recipients.PMID 23837477Read ↗

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