Article
The impact of interleukin 28B rs12979860 single nucleotide polymorphism and liver fibrosis stage on response-guided therapy in HIV/HCV-coinfected patients.
AIDS (London, England) - 13 Nov 2013
Mandorfer Mattias, Neukam Karin, Reiberger Thomas, Payer Berit A, Rivero Antonio, Puoti Massimo, Boesecke Christoph, Baumgarten Axel, Grzeszczuk Anna, Zangerle Robert, Meyer-Olson Dirk, Rockstroh Jürgen K, Trauner Michael, Pineda Juan A, Peck-Radosavljevic Markus
Abstract excerpt
OBJECTIVE: According to the European AIDS Clinical Society (EACS) guidelines for response-guided therapy (RGT) of chronic hepatitis C virus (HCV) infection in HIV-positive patients, HCV-genotype (GT) and rapid virologic response (RVR) exclusively determine the duration of antiviral therapy with pegylated interferon and ribavirin (PEGIFN+RBV). The aim of this study was to investigate the impact of interleukin 28B...
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