Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ca²+-binding properties and regulatory roles of lobster troponin C sites II and IV.

FEBS letters - 19 Aug 2013

Tanaka Hiroyuki, Takahashi Hiroki, Ojima Takao

Abstract excerpt

Invertebrate troponin C typically contains Ca²⁺-specific binding sites, sites II and IV, in the N- and C-terminal domains, respectively. To investigate the roles of these sites for Ca²⁺-dependent regulation of muscle contraction, we generated lobster troponin C mutants, and analyzed their Ca²⁺-binding properties and regulatory effects on actomyosin-tropomyosin Mg-ATPase activity. The results suggest that Ca²⁺...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Calcium
Share to Magnesium

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Muscle Contraction

Share to Protein Isoforms

Share to Recombinant Proteins

Share to Sequence Homology, Amino Acid

Share to Troponin C

Source

Identifiers

PMID: 23831063
DOI: 10.1016/j.febslet.2013.06.042

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ca²+-binding properties and regulatory roles of lobster troponin C sites II and IV.PMID 23831063Read ↗

Troponin-T is a calcium-binding protein in insect muscle: in vivo phosphorylation, muscle-specific isoforms and developmental profile in Drosophila melanogasterSemantic proximity Read ↗

Functional importance of Ca2+-deficient N-terminal lobe of molluscan troponin C in troponin regulation.Semantic proximity Read ↗

Inhibition of mutant troponin C activity by an intra-domain disulphide bond.Semantic proximity Read ↗

Structure-function relationship of muscle thin filament regulatory proteins : tropomyosin and troponinSemantic proximity Read ↗

Troponin C Mutations Partially Stabilize the Active State of Regulated Actin and Fully Stabilize the Active State When Paired with Δ14 TnT.Semantic proximity Read ↗

Troponin-C mutants with increased calcium affinity.Semantic proximity Read ↗

Intramolecular interactions in the N-domain of cardiac troponin C are important determinants of calcium sensitivity of force development.Semantic proximity Read ↗

The second half of the fourth period of tropomyosin is a key region for Ca(2+)-dependent regulation of striated muscle thin filaments.Semantic proximity Read ↗

Basic residues within the cardiac troponin T C terminus are required for full inhibition of muscle contraction and limit activation by calcium.Semantic proximity Read ↗

Roles for the troponin tail domain in thin filament assembly and regulation. A deletional study of cardiac troponin T.Semantic proximity Read ↗

Sequence mutations in teleost cardiac troponin C that are permissive of high Ca2+ affinity of site II.Semantic proximity Read ↗

Calcium-bindings of wild type and mutant troponin Cs of Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.