Phenotypic behavior of PBMCs from irradiated dogs based on flow cytometry.

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Article

Phenotypic behavior of PBMCs from irradiated dogs based on flow cytometry.

Journal of biological regulators and homeostatic agents - 1 Jan 2000

Toledo J M, Siqueira S L, Campos T P R, Falcao P L

Abstract excerpt

The present paper investigates the phenotypic parameters of stimulation markers and cell immunosuppression markers in an animal model using flow cytometry analysis. Six dogs were exposed to 2, 4 or 6 Gy following a head and neck protocol. Samples of peripheral blood mononuclear cells (PBMCs) were collected before irradiation, representing standard values for all dogs (control), and at 2 h, 18 h and 30 d after...

Topics

Animals
CTLA-4 Antigen
Dogs
Flow Cytometry
Leukocytes, Mononuclear
Male
Phenotype

Source

Open in PubMed

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PMID: 23830382

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