Article
Specific changes in peripheral blood lymphocyte phenotype from burn patients. Probable origin of the thermal injury-related lymphocytopenia.
Burns : journal of the International Society for Burn Injuries - 1 Jun 1991
Maldonado M D, Venturoli A, Franco A, Nunez-Roldan A
Abstract excerpt
T-lymphocyte subsets from 27 severely burned patients and 32 controls were analysed using monoclonal antibody immunofluorescent staining and flow cytometry. Compared to normal controls, burn patients showed a remarkable reduction in absolute number of CD3-lymphocytes in the 48 h following injury, which was accounted for by a decrease in both CD4 and CD8 subsets. Activated lymphocytes, as defined by expression of...
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