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Article

Etiopathogenesis of primary sclerosing cholangitis.

Seminars in liver disease - 1 Feb 2006

O'Mahony Christine A, Vierling John M

Abstract excerpt

The etiopathogenesis of primary sclerosing cholangitis (PSC) remains undefined. Immunopathogenetic mechanisms appear to be involved, based on human leukocyte antigen complex susceptibility associations, existence of multiple autoantibodies, and presence of inflammatory bowel disease in > 75% of patients. PSC may represent an autoimmune disease with atypical features or an immune-mediated inflammatory disease,...

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PMID: 16496229
DOI: 10.1055/s-2006-933559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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