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Article

The evolution of clonality testing in the diagnosis and monitoring of hematological malignancies

7 Feb 2014

Abstract excerpt

Currently, distinguishing between benign and malignant lymphoid proliferations is based on a combination of clinical characteristics, cyto/histomorphology, immunophenotype and the identification of well-defined chromosomal aberrations. However, such diagnoses remain challenging in 10-15% of cases of lymphoproliferative disorders, and clonality assessments are often required to confirm diagnostic suspicions. In...

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PMID: 24688753
DOI: 10.1177/2040620713519729

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