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Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degeneration

4 Jul 2013

Abstract excerpt

Although the link between altered stem cell properties and tissue aging has been recognized, the molecular and cellular processes of tendon aging have not been elucidated. As tendons contain stem/progenitor cells (TSPC), we investigated whether the molecular and cellular attributes of TSPC alter during tendon aging and degeneration. Comparing TSPC derived from young/healthy (Y-TSPC) and aged/degenerated human...

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PMID: 23826660
DOI: 10.1111/acel.12124

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