Article

Cellular and molecular landscapes of human tendons across the lifespan revealed by spatial and single-cell transcriptomics

2025-06-23

Abstract excerpt

<h4>SUMMARY</h4> Tendon injuries are common and often heal poorly. While developing tendons heal without scarring, this capacity declines with age, yet the underlying cellular transitions remain poorly defined. Here, we integrate histological, single-nucleus, single-cell, and spatial transcriptomic profiling of human Achilles and quadriceps tendons across embryonic, foetal, and adult stages, including ruptured ad...

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Literature Corpus work: 1ba36c30-b353-5cd7-8d13-25de391045ec
DOI: 10.1101/2025.06.19.660575

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