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Article

Integrated miRNA-mRNA Analysis Revealing the Potential Roles of miRNAs in Chordomas

24 Jun 2013

Abstract excerpt

INTRODUCTION: Emerging evidence suggests that microRNAs (miRNAs) are crucially involved in tumorigenesis and that paired expression profiles of miRNAs and mRNAs can be used to identify functional miRNA-target relationships with high precision. However, no studies have applied integrated analysis to miRNA and mRNA profiles in chordomas. The purpose of this study was to provide insights into the pathogenesis of...

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PMID: 23826111
DOI: 10.1371/journal.pone.0066676

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