Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Brachyury and chordoma: the chondroid–chordoid dilemma resolved?

7 Apr 2006

Abstract excerpt

Chordoma, and its relationship to the notochord, has intrigued many researchers over the last two centuries. In particular, the morphological overlap with cartilaginous tumours is striking, and developmental biology has shown a tight relationship between cartilage and the notochord. This is reflected in the expression of common genes in chordoid and chondroid tumours. Wide gene expression analyses have led to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Tumor Diagnosis and Treatments
Share to Cancer-related molecular mechanisms research
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16604512
DOI: 10.1002/path.1987

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Brachyury and chordoma: the chondroid–chordoid dilemma resolved?PMID 16604512Read ↗

Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomasSemantic proximity Read ↗

Transcriptional Profiling Supports the Notochordal Origin of Chordoma and Its Dependence on a TGFB1-TBXT NetworkSemantic proximity Read ↗

From Notochord Formation to Hereditary Chordoma: The Many Roles of<i>Brachyury</i>Semantic proximity Read ↗

Chordoma: Genetics and Contemporary Management.Semantic proximity Read ↗

Brachyury: A Diagnostic Marker for the Differential Diagnosis of Chordoma and Hemangioblastoma versus Neoplastic Histological MimickersSemantic proximity Read ↗

Brachyury expression is highly specific for chordoma: A tissue microarray study involving 14,976 cancers from 135 different tumor types and subtypesSemantic proximity Read ↗

The Roles of Embryonic Transcription Factor BRACHYURY in Tumorigenesis and ProgressionSemantic proximity Read ↗

Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular targetSemantic proximity Read ↗

Unraveling molecular advancements in chordoma tumorigenesis and treatment response: a review of scientific discoveries and clinical implicationsSemantic proximity Read ↗

Brachyury gene copy number gain and activation of the PI3K/Akt pathway: association with upregulation of oncogenic Brachyury expression in skull base chordomaSemantic proximity Read ↗

Epigenetic deregulations in chordomaSemantic proximity Read ↗

Integrated miRNA-mRNA Analysis Revealing the Potential Roles of miRNAs in ChordomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.