Article
Pharmacogenomic investigation of adverse drug reactions(ADRs): the ADR prioritization tool, APT.
Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique - 1 Jan 2013
Shaw Kaitlyn, Amstutz Ursula, Castro-Pastrana Lucila, Loo Tenneille T, Ross Colin J, Ito Shinya, Reider Michael J, Maher Maurica, Macleod Stuart, Koren Gideon, Hayden Michael R, Carleton Bruce C
Abstract excerpt
BACKGROUND: The impact of genetic factors on the risk of adverse drug reactions (ADRs) is being increasingly recognized as clinically important. ADR Prioritization Tool (APT) was developed to facilitate the prioritization of drugs and their associated ADRs for future pharmacogenomic studies. OBJECTIVES: To describe a novel tool developed for the prioritization of pharmacogenomic investigation of ADRs and discuss...
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