Article
Influence of the two-component system SaeRS on global gene expression in two different Staphylococcus aureus strains.
Journal of bacteriology - 1 Nov 2006
Rogasch Kathrin, Rühmling Vanessa, Pané-Farré Jan, Höper Dirk, Weinberg Christin, Fuchs Stephan, Schmudde Mareike, Bröker Barbara M, Wolz Christiane, Hecker Michael, Engelmann Susanne
Abstract excerpt
The two-component system SaeRS consisting of the histidin kinase SaeS and the response regulator SaeR is known to act on virulence gene expression in Staphylococcus aureus. In order to get a more comprehensive picture on SaeR-regulated genes, we studied the contribution of the two-component system on global gene expression by using both the proteomic and transcriptomic approach. Altogether, a loss of SaeRS...
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