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Article

Gene dosage of Otx2 is important for fertility in male mice.

Molecular and cellular endocrinology - 5 Sept 2013

Larder Rachel, Kimura Ikuo, Meadows Jason, Clark Daniel D, Mayo Susan, Mellon Pamela L

Abstract excerpt

Together, the hypothalamus, pituitary and gonads direct the development and regulation of reproductive function in mammals. Gonadotropin-releasing hormone (GnRH) expression is limited to ∼800 neurons that originate in the olfactory placode then migrate to the hypothalamus. Coordination of the hypothalamic-pituitary-gonadal (HPG) axis is dependent upon correct neuronal migration of GnRH neurons into the...

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Source

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Identifiers

PMID: 23811236
DOI: 10.1016/j.mce.2013.06.026
PMCID: PMC3771655

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Gene dosage of Otx2 is important for fertility in male mice.PMID 23811236Read ↗

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