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Article

Retinaldehyde dehydrogenase enzymes regulate colon enteric nervous system structure and function.

Developmental biology - 1 Sept 2013

Wright-Jin Elizabeth C, Grider John R, Duester Gregg, Heuckeroth Robert O

Abstract excerpt

The enteric nervous system (ENS) forms from the neural crest-derived precursors that colonize the bowel before differentiating into a network of neurons and glia that control intestinal function. Retinoids are essential for normal ENS development, but the role of retinoic acid (RA) metabolism in development remains incompletely understood. Because RA is produced locally in the tissues where it acts by stimulating...

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Identifiers

PMID: 23806210
DOI: 10.1016/j.ydbio.2013.06.021
PMCID: PMC3745936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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