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Article

A robust immunoassay for pregnancy-associated plasma protein-A2 based on analysis of circulating antigen: establishment of normal ranges in pregnancy

25 Jun 2013

Abstract excerpt

Pregnancy-associated plasma protein-A (PAPP-A) and PAPP-A2, two homologous metzincin metalloproteases, are both tightly linked to regulation within the insulin-like growth factor (IGF) system because of their specific cleavage of IGF binding proteins. Recent studies suggest that PAPP-A may be involved in clinical conditions related to unwanted cellular growth, and the circulating levels of PAPP-A is an...

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Growth Hormone and Insulin-like Growth Factors
Prenatal Screening and Diagnostics
Renal and related cancers

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23804707
DOI: 10.1093/molehr/gat047

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A robust immunoassay for pregnancy-associated plasma protein-A2 based on analysis of circulating antigen: establishment of normal ranges in pregnancyPMID 23804707Read ↗

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Expression of pregnancy-associated plasma protein A2 during pregnancy in human and mouseSemantic proximity Read ↗

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