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Article

Association of MMP1-1607 1G/2G and TIMP1 372 T/C gene polymorphisms with risk of primary open angle glaucoma in a Polish population.

Medical science monitor : international medical journal of experimental and clinical research - 1 Jul 2011

Majsterek Ireneusz, Markiewicz Lukasz, Przybylowska Karolina, Gacek Mira, Kurowska Anna K, Kaminska Anna, Szaflik Jerzy, Szaflik Jacek P

Abstract excerpt

BACKGROUND: Primary open angle glaucoma (POAG) is considered to be a leading cause of irreversible blindness worldwide. Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) have been extensively studied as POAG risk factors. Recently, several single-nucleotide polymorphisms (SNPs) for MMPs and TIMPs encoding genes have been reported in POAG patients. The aim of this study was to investigate association...

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Source

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Identifiers

PMID: 21709637
DOI: 10.12659/msm.881854
PMCID: PMC3539563

Genes

MMP1
TIMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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