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Article

Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies.

Translational psychiatry - 25 Jun 2013

Nurmi E L, Spilman S L, Whelan F, Scahill L L, Aman M G, McDougle C J, Arnold L E, Handen B, Johnson C, Sukhodolsky D G, Posey D J, Lecavalier L, Stigler K A, Ritz L, Tierney E, Vitiello B, McCracken J T

Abstract excerpt

Second-generation antipsychotic exposure, in both children and adults, carries significant risk for excessive weight gain that varies widely across individuals. We queried common variation in key energy balance genes (FTO, MC4R, LEP, CNR1, FAAH) for their association with weight gain during the i...

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Share to Amidohydrolases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antipsychotic Agents

Share to Child Development Disorders, Pervasive

Share to Receptor, Cannabinoid, CB1

Share to Receptor, Melanocortin, Type 4

Share to Risperidone

Share to Weight Gain

Source

Open in PubMed Open full text

Identifiers

PMID: 23799528
DOI: 10.1038/tp.2013.26
PMCID: PMC3693401

Genes

CNR1
FTO
LEP
FAAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23799528-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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