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Dynamics of DNA Methylation during Early Development of the Preimplantation Bovine Embryo

14 Jun 2013

Abstract excerpt

There is species divergence in control of DNA methylation during preimplantation development. The exact pattern of methylation in the bovine embryo has not been established nor has its regulation by gender or maternal signals that regulate development such as colony stimulating factor 2 (CSF2). Using immunofluorescent labeling with anti-5-methylcytosine and embryos produced with X-chromosome sorted sperm, it was...

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PMID: 23799080
DOI: 10.1371/journal.pone.0066230

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