Article
Recent advances in Parkinson’s disease genetics.
Journal of neurology - 1 Feb 2014
Lubbe Steven, Morris Huw R
Abstract excerpt
The last 5 years have seen rapid progress in Parkinson’s disease (PD) genetics, with the publication of a series of large-scale genome wide association studies for PD, and evaluation of the roles of the LRRK2 and GBA genes in the aetiology of PD. We are beginning to develop a coherent picture of the interplay of Mendelian and non-Mendelian factors in PD. Pathways involved in mitochondrial quality control...
Topics
- Gene Frequency
- Genes, Dominant
- Genes, Recessive
- Genetic Variation
- Genome-Wide Association Study
- Humans
- Parkinson Disease
