Article
Association of epidermal growth factor receptor mutations with human papillomavirus 16/18 E6 oncoprotein expression in non-small cell lung cancer.
Cancer - 15 Sept 2013
Tung Min-Che, Wu Heng-Hsiung, Cheng Ya-Wen, Wang Lee, Chen Chih-Yi, Yeh Sauh-Der, Wu Tzu-Chin, Lee Huei
Abstract excerpt
BACKGROUND: Lung cancers in women, in nonsmokers, and in patients with adenocarcinoma from Asia have more prevalent mutations in the epidermal growth factor receptor (EGFR) gene than their counterparts. However, the etiology of EGFR mutations in this population remains unclear. The authors hypothesized that the human papillomavirus (HPV) type 16/18 (HPV16/18) E6 oncoprotein may contribute to EGFR mutations in...
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