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Article

Higher homocysteine and lower betaine increase the risk of microangiopathy in patients with diabetes mellitus carrying the GG genotype of PEMT G774C.

Diabetes/metabolism research and reviews - 1 Nov 2013

Chen Li, Chen Yan-ming, Wang Li-jun, Wei Jun, Tan Yao-zong, Zhou Jing-ya, Yang Yang, Chen Yu-ming, Ling Wen-hua, Zhu Hui-lian

Abstract excerpt

BACKGROUND: Diabetes represents one of the greatest medical and socioeconomic threats worldwide. The pathogenesis involved is complicated. The effect of methyl donors and genetic polymorphisms in metabolic enzymes on the risk of microangiopathy in patients with diabetes is not well understood. Th...

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Source

Identifiers

PMID: 23794489
DOI: 10.1002/dmrr.2432

Genes

PEMT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23794489-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Higher homocysteine and lower betaine increase the risk of microangiopathy in patients with diabetes mellitus carrying the GG genotype of PEMT G774C.PMID 23794489Read ↗

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