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Article

Genome-Wide Variation of Cytosine Modifications Between European and African Populations and the Implications for Complex Traits

22 Jun 2013

Abstract excerpt

Elucidating cytosine modification differences between human populations can enhance our understanding of ethnic specificity in complex traits. In this study, cytosine modification levels in 133 HapMap lymphoblastoid cell lines derived from individuals of European or African ancestry were profiled using the Illumina HumanMethylation450 BeadChip. Approximately 13% of the analyzed CpG sites showed differential...

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PMID: 23792949
DOI: 10.1534/genetics.113.151381

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