Article
Pharmacogenetic predictors of nausea and vomiting of pregnancy severity and response to antiemetic therapy: a pilot study.
BMC pregnancy and childbirth - 20 Jun 2013
Lehmann Amalia S, Renbarger Jamie L, McCormick Catherine L, Topletz Ariel R, Rouse Carrie, Haas David M
Abstract excerpt
BACKGROUND: Nausea and vomiting of pregnancy (NVP) is a common condition. The objective of this study was to evaluate the association between response to antiemetics in the treatment of NVP and genetic polymorphisms in the serotonin receptor subunit genes HTR3A and HTR3B. METHODS: Pregnant women ≥18 years of age with NVP starting antiemetic therapy with promethazine, prochlorperazine, metoclopramide, or...
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