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Article

Somatic MYH7, MYBPC3, TPM1, TNNT2 and TNNI3 mutations in sporadic hypertrophic cardiomyopathy.

Circulation journal : official journal of the Japanese Circulation Society - 1 Jan 2013

Núñez Lucía, Gimeno-Blanes Juan Ramón, Rodríguez-García María Isabel, Monserrat Lorenzo, Zorio Esther, Coats Caroline, McGregor Christopher G, Hernandez del Rincón Juan Pedro, Castro-Beiras Alfonso, Hermida-Prieto Manuel

Abstract excerpt

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a clinically heterogeneous genetic heart disease characterized by left ventricular hypertrophy in the absence of another disease that could explain the wall thickening. Elucidation of the genetic basis of HCM lead to the identification of several genes encoding sarcomeric proteins, such as MYH7, MYBPC3, TPM1, TNNT2, and TNNI3. Sarcomeric genes are mutated in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23782526
DOI: 10.1253/circj.cj-13-0294

Genes

MYBPC3
MYH7
TNNI3
TNNT2
TPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Somatic MYH7, MYBPC3, TPM1, TNNT2 and TNNI3 mutations in sporadic hypertrophic cardiomyopathy.PMID 23782526Read ↗

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