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Article

EGFR mutations detected on cytology samples by a centralized laboratory reliably predict response to gefitinib in non-small cell lung carcinoma patients.

Cancer cytopathology - 1 Oct 2013

Malapelle Umberto, Bellevicine Claudio, De Luca Caterina, Salatiello Maria, De Stefano Alfonso, Rocco Danilo, de Rosa Nicla, Vitiello Fabiana, Russo Stefania, Pepe Francesco, Iaccarino Antonino, Micheli Pietro, Illiano Alfonso, Carlomagno Chiara, Piantedosi Franco Vito, Troncone Giancarlo

Abstract excerpt

BACKGROUND: Epidermal growth factor receptor (EGFR) mutations are reliably detected by referral laboratories, even if most lung cancer cytology specimens sent to such laboratories contain very few cells. However, EGFR mutations may be distributed heterogeneously within tumors, thereby raising con...

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Source

Identifiers

PMID: 23780873
DOI: 10.1002/cncy.21322

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23780873-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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