Article
Molecular detection and typing of human papillomavirus in laryngeal carcinoma specimens.
Acta oto-laryngologica - 1 Aug 2005
Torrente Mariela C, Ampuero Sandra, Abud Maritza, Ojeda Jose M
Abstract excerpt
CONCLUSIONS: Human papillomavirus (HPV) DNA was detected in 32% of laryngeal carcinoma biopsy samples studied. The genotypes identified were high-risk types, the most frequent being HPV 16. Viral DNA was integrated into the host genome (genotype HPV 16), providing supporting evidence for a role of HPV in the carcinogenic pathway of laryngeal squamous cell carcinoma. OBJECTIVE: HPV has been detected in laryngeal...
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