Article
High-risk HPV genotypes and P16INK4a expression in a cohort of head and neck squamous cell carcinoma patients in Singapore.
Oncotarget - 27 Dec 2016
Tan Louise Soo Yee, Fredrik Petersson, Ker Liang, Yu Feng Gang, Wang De Yun, Goh Boon Cher, Loh Kwok Seng, Lim Chwee Ming
Abstract excerpt
Human papillomavirus (HPV), especially HPV16 genotype, is associated with oropharyngeal squamous cell carcinoma (OPSCC). We aim to determine the prevalence and characterize the high-risk (HR)-HPV genotypes in head and neck SCC (HNSCC) in a South-East Asian multi-ethnic society in Singapore and examine its prognostic significance.159 HNSCC archival tissue samples were retrieved and tumour DNA was screened for 18...
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