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Troponin T3 expression in skeletal and smooth muscle is required for growth and postnatal survival: characterization of Tnnt3(tm2a(KOMP)Wtsi) mice.

Genesis (New York, N.Y. : 2000) - 1 Sept 2013

Ju Yawen, Li Jie, Xie Chao, Ritchlin Christopher T, Xing Lianping, Hilton Matthew J, Schwarz Edward M

Abstract excerpt

The troponin complex, which consists of three regulatory proteins (troponin C, troponin I, and troponin T), is known to regulate muscle contraction in skeletal and cardiac muscle, but its role in smooth muscle remains controversial. Troponin T3 (TnnT3) is a fast skeletal muscle troponin believed to be expressed only in skeletal muscle cells. To determine the in vivo function and tissue-specific expression of...

Topics

Animals
Kidney
Liver
Mice
Mice, Inbred C57BL
Mice, Knockout
Muscle, Skeletal
Muscle, Smooth
Phenotype
Transgenes
Troponin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Troponin T

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Identifiers

PMID: 23775847
DOI: 10.1002/dvg.22407
PMCID: PMC3787964

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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