Article
Association between a common CYP17A1 haplotype and anxiety in female anorexia nervosa.
Archives of women's mental health - 1 Oct 2013
Czerniak Efrat, Korostishevsky Michael, Frisch Amos, Cohen Yoram, Amariglio Ninette, Rechavi Gideon, Michaelovsky Elena, Stein Daniel, Danziger Yardena, Fennig Silvana, Apter Alan, Weizman Abraham, Gak Eva
Abstract excerpt
Dehydroepiandrosterone (DHEA), the main brain neurosteroid, has been implicated in various psychiatric disorders especially those including gender differences. We studied genetic variability in the DHEA-producing enzyme CYP17A1 in relation to anorexia nervosa (AN) susceptibility and AN-related co-morbidities. We performed analysis of 100 Israeli AN family trios accounting for CYP17A1 haplotypes characteristic of...
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