Article
The glomerular basement membrane as a barrier to albumin.
Nature reviews. Nephrology - 1 Aug 2013
Suh Jung Hee, Miner Jeffrey H
Abstract excerpt
The glomerular basement membrane (GBM) is the central, non-cellular layer of the glomerular filtration barrier that is situated between the two cellular components--fenestrated endothelial cells and interdigitated podocyte foot processes. The GBM is composed primarily of four types of extracellular matrix macromolecule--laminin-521, type IV collagen α3α4α5, the heparan sulphate proteoglycan agrin, and...
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