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Article

Localization, not important in all tumor-suppressing properties: a lesson learnt from scribble.

Cells, tissues, organs - 1 Jan 2013

Elsum Imogen A, Humbert Patrick O

Abstract excerpt

Aberrant localization of proteins is increasingly being suggested as a causal player in epithelial cancers. Despite this, few studies have investigated how mislocalization of a protein can alter individual biological processes that contribute to cancer progression. Using Ras as a model of transformation, we investigate how localization of the polarity protein Scribble contributes to its tumor-suppressive...

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Share to Cell Proliferation
Share to Epidermal Growth Factor
Share to Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MAP Kinase Signaling System

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Source

Identifiers

PMID: 23774808
DOI: 10.1159/000348423

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Localization, not important in all tumor-suppressing properties: a lesson learnt from scribble.PMID 23774808Read ↗

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