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Proton Pump Inhibitors in Gastroesophageal Reflux Disease: Friend or Foe.

Current gastroenterology reports - 1 Sept 2017

Gyawali C Prakash

Abstract excerpt

PURPOSE OF REVIEW: Proton pump inhibitor (PPI) use in gastroesophageal reflux disease (GERD) has been redefined, in light of recent advances highlighting GERD phenotypes that respond to PPIs, and fresh revelations of potential risks of long-term PPI therapy. RECENT FINDINGS: Erosive esophagitis predicts excellent response to PPI therapy, but non-erosive reflux disease (NERD) with abnormal reflux parameters on...

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Gastroesophageal Reflux
Genotype
Proton Pump Inhibitors
Risk
Treatment Outcome

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PMID: 28780717
DOI: 10.1007/s11894-017-0586-5

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