Article
Th17 Cells as Potential Probiotic Therapeutic Targets in Inflammatory Bowel Diseases.
International journal of molecular sciences - 1 Sept 2015
Owaga Eddy, Hsieh Rong-Hong, Mugendi Beatrice, Masuku Sakhile, Shih Chun-Kuang, Chang Jung-Su
Abstract excerpt
Inflammatory bowel diseases (IBD) are characterized by wasting and chronic intestinal inflammation triggered by various cytokine-mediated pathways. In recent years, it was shown that T helper 17 (Th17) cells are involved in the pathogenesis of IBD, which makes them an attractive therapeutic target. Th17 cells preferentially produce interleukin (IL)-17A-F as signature cytokines. The role of the interplay between...
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