Article
Special considerations in prognostic research in cancer involving genetic polymorphisms.
BMC medicine - 17 Jun 2013
Savas Sevtap, Liu Geoffrey, Xu Wei
Abstract excerpt
Analysis of genetic polymorphisms may help identify putative prognostic markers and determine the biological basis of variable prognosis in patients. However, in contrast to other variables commonly used in the prognostic studies, there are special considerations when studying genetic polymorphisms. For example, variable inheritance patterns (recessive, dominant, codominant, and additive genetic models) need to...
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