Article
PSORS1C1 may be involved in rheumatoid arthritis.
Immunology letters - 1 Jun 2013
Sun Hongjun, Xia Yifang, Wang Lin, Wang Yuejian, Chang Xiaotian
Abstract excerpt
PSORS1C1/CDSN is a susceptibility gene for psoriasis. Both psoriasis and rheumatoid arthritis (RA) are autoimmune diseases. This study investigated whether PSORS1C1/CDSN was involved in RA. The TagSNPs rs3130983, rs3778638 and rs4959053 in the PSORS1C1/CDSN locus were shown to predict susceptibility to RA in two independent RA cohorts using a TaqMan genotyping assay and Sequenom MassARRAY. The expression of...
Read the complete abstract on PubMed