Article
Admixture analysis of age at onset in obsessive-compulsive disorder.
Psychological medicine - 1 Feb 2005
Delorme Richard, Golmard Jean-Louis, Chabane Nadia, Millet Bruno, Krebs Marie-Odile, Mouren-Simeoni Marie Christine, Leboyer Marion
Abstract excerpt
BACKGROUND: Age at onset (AAO) has been useful to explore the clinical, neurobiological and genetic heterogeneity of obsessive-compulsive disorder (OCD). However, none of the various thresholds of AAO used in previous studies have been validated, and it remains an unproven notion that AAO is a marker for different subtypes of OCD. If AAO is a clinical indicator of different biological subtypes, then subgroups...
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