[The effect of corticosteroid on lymphokine-activated killer (LAK) activity and the change of membrane antigen phenotype on PBMC after IL2 incubation with reference to the evaluation in vitro].

Abstract excerpt

In the treatment of human cancer, the efficacy of the adoptive transfer of lymphokine-activated killer (LAK) cells combined with interleukin 2 (IL2) has been emphasized. However, administration of large doses of IL2 may cause significant adverse effects, such as "capillary leak syndrome". Moreover, the administration of corticosteroid may reduce the toxicity of IL2. However the efficacy of adoptive immunotherapy...

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