Article
[The effect of corticosteroid on lymphokine-activated killer (LAK) activity and the change of membrane antigen phenotype on PBMC after IL2 incubation with reference to the evaluation in vitro].
Nihon Ika Daigaku zasshi - 1 Jun 1990
Yoshimura A
Abstract excerpt
In the treatment of human cancer, the efficacy of the adoptive transfer of lymphokine-activated killer (LAK) cells combined with interleukin 2 (IL2) has been emphasized. However, administration of large doses of IL2 may cause significant adverse effects, such as "capillary leak syndrome". Moreove...
Topics
- Antigens, Surface
- Cells, Cultured
- HLA-DR Antigens
- Humans
- Immunization, Passive
- Interleukin-2
- Killer Cells, Lymphokine-Activated
- Leukocytes, Mononuclear
- Lymphocyte Activation
- Methylprednisolone
- Phenotype
