Article
SNPs in inflammatory genes CCL11, CCL4 and MEFV in a fibromyalgia family study.
PloS one - 1 Jan 2018
Zhang Zhifang, Feng Jinong, Mao Allen, Le Keith, La Placa Deirdre, Wu Xiwei, Longmate Jeffrey, Marek Claudia, St Amand R Paul, Neuhausen Susan L, Shively John E
Abstract excerpt
BACKGROUND: Fibromyalgia (FM) is a chronic pain syndrome with a high incidence in females that may involve activation of the immune system. We performed exome sequencing on chemokine genes in a region of chromosome 17 identified in a genome-wide family association study. METHODS AND FINDINGS: Exome sequence analysis of 100 FM probands was performed at 17p13.3-q25 followed by functional analysis of SNPs found in...
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