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Article

ATP interacts with the CPVT mutation-associated central domain of the cardiac ryanodine receptor.

Biochimica et biophysica acta - 1 Oct 2013

Blayney Lynda, Beck Konrad, MacDonald Ewan, D'Cruz Leon, Nomikos Michail, Griffiths Julia, Thanassoulas Angelos, Nounesis George, Lai F Anthony

Abstract excerpt

BACKGROUND: This study was designed to determine whether the cardiac ryanodine receptor (RyR2) central domain, a region associated with catecholamine polymorphic ventricular tachycardia (CPVT) mutations, interacts with the RyR2 regulators, ATP and the FK506-binding protein 12.6 (FKBP12.6). METHOD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23747301
DOI: 10.1016/j.bbagen.2013.05.038

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-23747301-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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