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Article

Glycan receptor binding of the influenza A virus H7N9 hemagglutinin.

Cell - 20 Jun 2013

Tharakaraman Kannan, Jayaraman Akila, Raman Rahul, Viswanathan Karthik, Stebbins Nathan W, Johnson David, Shriver Zachary, Sasisekharan V, Sasisekharan Ram

Abstract excerpt

The advent of H7N9 in early 2013 is of concern for a number of reasons, including its capability to infect humans, the lack of clarity in the etiology of infection, and because the human population does not have pre-existing immunity to the H7 subtype. Earlier sequence analyses of H7N9 hemagglutinin (HA) point to amino acid changes that predicted human receptor binding and impinge on the antigenic characteristics...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23746830
DOI: 10.1016/j.cell.2013.05.034
PMCID: PMC3746546

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