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Potassium channel activation inhibits proliferation of breast cancer cells by activating a senescence program

6 Jun 2013

Abstract excerpt

Traditionally the hERG1 potassium channel has been known to have a fundamental role in membrane excitability of several mammalian cells including cardiac myocytes. hERG1 has recently been found to be expressed in non-excitable cancer cells of different histogenesis, but the role of this channel in cancer biology is unknown. Results form recent studies on the effect hERG1 inhibition in some breast cancer cells are...

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PMID: 23744352
DOI: 10.1038/cddis.2013.174

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