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Article

Ether a go-go Potassium Channels as Human Cervical Cancer Markers

1 Oct 2004

Abstract excerpt

Ether a go-go (EAG) potassium channels display oncogenic properties. In normal tissues, EAG mRNA is almost exclusively expressed in brain, but it is expressed in several somatic cancer cell lines, including HeLa, from cervix. Antisense experiments against eag reduce cell proliferation in some cancer cell lines, and inhibition of EAG-mediated currents has been suggested to decrease cell proliferation in a melanoma...

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PMID: 15466192
DOI: 10.1158/0008-5472.can-04-1204

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