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Article

Eicosanoid biosynthesis during mucociliary and mucous metaplastic differentiation of bronchial epithelial cells.

Prostaglandins & other lipid mediators - 1 Oct 2013

Jakiela Bogdan, Gielicz Anna, Plutecka Hanna, Hubalewska Magdalena, Mastalerz Lucyna, Bochenek Grazyna, Soja Jerzy, Januszek Rafal, Musial Jacek, Sanak Marek

Abstract excerpt

The purpose of this study was to examine the profile of eicosanoids secreted by human bronchial epithelial cells (HBEC) during their in vitro differentiation toward mucociliary or mucous metaplastic phenotype. Eicosanoids were measured in supernatants by mass spectrometry, and corresponding gene expression by real-time PCR. Primary HBEC produced mainly prostaglandins (PGE2, PGD2) and epoxides (e.g. 14,15-EET),...

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Identifiers

PMID: 23742951
DOI: 10.1016/j.prostaglandins.2013.05.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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