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Investigation of The Relationship Between IL-18 (-607 C/A), IL-18 (-137 G/C) Gene Variations and Ischemic Stroke Disease Development in Thrace Region of Turkey.

Immunological investigations - 1 Aug 2021

Alkanli Nevra, Ay Arzu, Kehaya Sezgin, Sut Necdet

Abstract excerpt

BACKGROUND: Ischemic stroke is a clinical condition characterized by focal or global cerebral dysfunction resulting from inhibition of brain blood flow. Genetic factors play an important role in the pathogenesis of ischemic stroke. As a result of IL-18 (-607 C/A, -137 G/C) gene variations, it is thought that binding of transcription factors may be affected and IL-18 mRNA expression can be modulated. Therefore,...

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PMID: 32573302
DOI: 10.1080/08820139.2020.1782932

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