Article
The vir locus affects the response of Bordetella pertussis to antibiotics: phenotypic tolerance and control of autolysis.
The Journal of infectious diseases - 1 Aug 1990
Tuomanen E, Schwartz J, Sande S
Abstract excerpt
Eradication of Bordetella pertussis from the respiratory tract occurs slowly even when bactericidal antibiotics are used. The rate of killing of B. pertussis was found to be proportional to growth rate: virulent, slowly growing strains were killed over days, while rapidly growing strains (either...
Topics
- Anti-Bacterial Agents
- Bacterial Proteins
- Bacteriolysis
- Bordetella pertussis
- Carrier Proteins
- Cell Wall
- Densitometry
- Hexosyltransferases
- Humans
- Lactams
- Microscopy, Electron
- Molecular Weight
- Muramoylpentapeptide Carboxypeptidase
- Penicillin-Binding Proteins
- Peptidoglycan
- Peptidyl Transferases
- Phenotype
- Virulence