Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Restrictions to HIV-1 replication in resting CD4+ T lymphocytes

4 Jun 2013

Abstract excerpt

CD4(+) T lymphocytes represent the main target cell population of human immunodeficiency virus (HIV). In an activated state, CD4(+) T cells residing in lymphoid organs are a major reservoir of ongoing HIV-1 replication in infected individuals. In contrast, resting CD4(+) T cells are highly resistant to productive HIV-1 infection, yet are massively depleted during disease progression and represent a substantial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to HIV Research and Treatment
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23732522
DOI: 10.1038/cr.2013.74

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Restrictions to HIV-1 replication in resting CD4+ T lymphocytesPMID 23732522Read ↗

SAMHD1: a new contributor to HIV-1 restriction in resting CD4+T-cellsSemantic proximity Read ↗

The trinity of the cortical actin in the initiation of HIV-1 infectionSemantic proximity Read ↗

SAMHD1 restricts HIV-1 infection in resting CD4+ T cellsSemantic proximity Read ↗

Restriction Factors: From Intrinsic Viral Restriction to Shaping Cellular Immunity Against HIV-1Semantic proximity Read ↗

Restriction Factors in HIV-1 Disease ProgressionSemantic proximity Read ↗

HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells.Semantic proximity Read ↗

PSGL-1 inhibits HIV-1 infection by restricting actin dynamics and sequestering HIV envelope proteinsSemantic proximity Read ↗

The Dynamic Interplay between HIV-1, SAMHD1, and the Innate Antiviral ResponseSemantic proximity Read ↗

The Restriction Factors of Human Immunodeficiency VirusSemantic proximity Read ↗

HIV-1 Latency and Viral Reservoirs: Existing Reversal Approaches and Potential Technologies, Targets, and Pathways Involved in HIV Latency StudiesSemantic proximity Read ↗

How HIV Takes Advantage of the Cytoskeleton in Entry and ReplicationSemantic proximity Read ↗

The Molecular Basis for Human Immunodeficiency Virus LatencySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.