Article
Effect of genetic polymorphisms on development of gout.
The Journal of rheumatology - 1 Aug 2013
Urano Wako, Taniguchi Atsuo, Inoue Eisuke, Sekita Chieko, Ichikawa Naomi, Koseki Yumi, Kamatani Naoyuki, Yamanaka Hisashi
Abstract excerpt
OBJECTIVE: To validate the association between genetic polymorphisms and gout in Japanese patients, and to investigate the cumulative effects of multiple genetic factors on the development of gout. METHODS: Subjects were 153 Japanese male patients with gout and 532 male controls. The genotypes of 11 polymorphisms in the 10 genes that have been indicated to be associated with serum uric acid levels or gout were...
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