Article
Characterization and regulation of sex-specific mouse steroid hydroxylase genes.
Canadian journal of physiology and pharmacology - 1 Jun 1990
Yoshioka H, Lindberg R, Wong G, Ichikawa T, Itakura T, Burkhart B, Negishi M
Abstract excerpt
We characterized the genes of the male-specific mouse steroid 16 alpha-hydroxylase (C-P-45016 alpha) and the female-specific mouse steroid 15 alpha-hydroxylase (P-45015 alpha) within two distinct gene families. In spite of the high structural identities within each family, the expression of the h...
Topics
- Amino Acid Sequence
- Animals
- Aryl Hydrocarbon Hydroxylases
- Base Sequence
- Cloning, Molecular
- Coumarins
- Cytochrome P-450 CYP2A6
- Cytochrome P-450 Enzyme System
- DNA
- Enzyme Induction
- Female
- Gene Expression Regulation, Enzymologic
- Male
- Mice
- Mixed Function Oxygenases
- Molecular Sequence Data
- Mutation
- Sex Characteristics