Article
Characterization and regulation of sex-specific mouse steroid hydroxylase genes.
Canadian journal of physiology and pharmacology - 1 Jun 1990
Yoshioka H, Lindberg R, Wong G, Ichikawa T, Itakura T, Burkhart B, Negishi M
Abstract excerpt
We characterized the genes of the male-specific mouse steroid 16 alpha-hydroxylase (C-P-45016 alpha) and the female-specific mouse steroid 15 alpha-hydroxylase (P-45015 alpha) within two distinct gene families. In spite of the high structural identities within each family, the expression of the hydroxylase genes is uniquely regulated. Moreover, the other family members encode the P-450s which are structurally...
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